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The Bitter Truth About Sugar with Prof Robert Lustig

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The Bitter Truth About Sugar with Prof Robert Lustig

Sugar is responsible for a global health crisis!

The evidence can no longer be ignored, sugar is to blame for the continual rise in chronic disease. Prof Robert Lustig is a paediatric neuroendocrinologist, researcher, clinician and pioneer of the anti-sugar movement.

Today Prof Lustig takes us through his expansive career and how he became a global leader in teaching both peers and public of the perils of sugar, fructose and carbohydrates; and the roles they play in the pathogenesis of disease.


Covered in this episode:

[01:32] Introducing Prof Robert Lustig
[03:12] Prof Lustig discusses his professional and academic career
[06:00] What made Prof Lustig pursue sugar
[08:54] Drug therapy to reduce insulin
[09:45] Biochemistry drives behaviour
[12:34] Insulin hypersecretion vs insulin resistance
[14:50] Personalised obesity medicine
[15:30] Alpha Melanocyte Stimulating Hormone 
[17:45] Leptin resistance
[19:11] Why weightloss slows over time
[22:46] The low-fat diet doesn’t work
[23:50] The mechanisms of carbs and sugar
[24:33] Why there's a pandemic of NAFLD, even in children
[25:22] The Ansell Keys' fat legacy
[30:11] Not all sugar is created equal?
[31:06] The power of fibre
[35:08] Glycemic Index vs. Glycemic Load
[38:00] Impact of fructose for Type 1 Diabetes
[41:37] Fructose: pathology and testing to consider
[43:56] Prof Lustig's 2-Hit Theory
[47:37] Devils Advocate: Australia doesn’t have HFCS
[48:59] Mitochondrial transcription factors: sertuin 1, 3
[49:50] How practitioners can categorize the obese patient
[52:16] Teaching patients about food
[55:06] Modifiable factors
[57:32] Do we need to say goodbye to sugar?
[59:42] Final question: what resources can we direct people to?
[1:04:38] See Prof Lustig at the 5th BioCeuticals Research Symposium

Research Explored in this podcast

Lim J, Mietus-Snyder M, Valente A, et al. The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome. Nat Rev Gastroenterol Hepatol 2010 May; 7(5):251-264 

Additional Resources

Dr Robert Lustig | USCF Profile 
Sugar Science: The unsweetened truth
Book: Fat Chance, by Prof Robert Lustig
Book: Fat Chance Cookbook, by Prof Robert Lustig
Institute for Responsible Nutrition
Sperling: Paediatric Endocrinology, 3rd Ed. 
Documentary: Fed Up
Documentary: Sugar Coated
Documentary: That Sugar Film


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FX Medicine Podcast
FX Medicine is at the forefront of ensuring functional and integrative medicine gains the recognition it deserves and ultimately establishes itself as an integral part of standard medical practice. Hosted by Andrew Whitfield-Cook, our podcasts are designed to promote research and evidence-based therapeutic practises, acting as a progressive force for change and improvement in patient health and wellbeing.