Functional Pathology: Neurotransmitters with Beth Bundy

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Functional Pathology: Neurotransmitters with Beth Bundy

Detecting neurotransmitter (NT) imbalance has the potential to refine treatment choices for sufferers of depression, anxiety, insomnia and chronic pain.

Although it is not yet possible to measure NTs directly within the central nervous system (CNS), newer research proposes that testing for NT metabolites in our urine may offer up some clues as to what it happening in the CNS.

Today, naturopath and functional pathology expert Beth Bundy helps us to navigate the clinical relevance of using this sphere of testing. Whilst only a guide, to be used alongside other assessments, perhaps this form of testing will reduce the guesswork and improve the success rate of initial treatment above the 50% chance for current pharmacological management?

Covered in this episode:

[01:10] Welcoming back Beth Bundy
[02:21] Today's Topic: Neurotransmitter Testing
[02:39] The role of neurotransmitters
[03:45] Circulation and transport of neurotransmitters
[04:43] Evidence of testing 
[05:54] Are we testing actual neurotransmitters or metabolites?
[06:04] Inhibitory Neurotransmitters
[06:11] Excitatory Neurotransmitters
[06:16] Glutamate 
[06:40] Dopamine and metabolites
[07:10] Adrenaline, Nor Adrenaline and metabolites
[08:01] Serotonin and metabolites
[08:18] GABA
[08:25] Glycine
[08:55] Phenethylamine (PEA) 
[10:03] Limitations and influencers on testing
[15:44] Not a stand alone test
[18:04] Clinical significance of the tests
[20:37] Applying neurotransmitter testing
[30:57] Performing the test(s)
[36:35] When would you not do a neurotransmitter test?
[38:15] Final summary 

Additional Resources

Other podcasts with Beth include:


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Beth Bundy
Beth Bundy is a qualified Naturopath with over 15 years specialising in integrative and functional medicine. She plays a role in the clinical training programs and educational initiatives to offer the most advanced clinical tools available to prevent and treat the underlying causes of disease. Beth obtained her Bachelor of Health Science at the Southern School of Natural Therapies and lectured in both Nutrition and Food as Medicine for several years at the Australian College of Natural Medicine (now Endeavour College). She has worked as Technical and Practitioner Consultant with one of Australia’s top functional pathology companies where she was mentor here and overseas by some of integrative and anti-ageing medicines foremost speakers. She has operated her own business and currently also works in a busy and highly successful integrative medical practice which specialises in adrenal and hormonal issues, along with weight management and heavy metal detoxification, with a strong emphasis on functional pathology to assist clinical treatment. Additionally, she is a Clinical Consultant at NutriPATH Integrative Pathology Services. Beth provides friendly and expert clinical training and support to assist practitioners in choosing the most appropriate test profiles, interpreting test results, and offering guidance on treatment approaches.