Through his personal journey with Rheumatoid Arthritis (RA), Clint Paddison knows only too well just how debilitating and challenging RA can be. This led him to develop "The Paddison Program", a new, and somewhat controversial approach that challenges the status-quo of accepted evidence in complementary medicine.
Following his own diagnosis he found himself confined to his bed and robbed of his usual physically active lifestyle. Clint immersed himself in RA research and through his own personal trial and error, he developed protocols that helped reverse his disease. The results are nothing short of incredible, and he's gone on to teach thousands of other's his methods and help them too, gain control over this degenerative condition.
Covered in this episode
[02:05] Meet Clint Paddison
[03:08] Delving into Clint's history
[06:55] What symptoms were the first sign that something was wrong?
[09:29] Understanding the inflammatory process of RA
[12:07] Rheumatoid Arthritis is notoriously hard to treat. Clint has virtually tried them all.
[14:47] The food needs to be right first.
[19:22] The Paddison Program
[20:40] Lessons from a bout of food poisoning.
[24:19] The role of bacteria
[25:49] The "Bulls-Eye" - The problem is fat.
[31:13] "B.L.A.A.M.E" - The cause.
[33:26] How strict do the dietary interventions need to be?
[38:30] Future hope: the co-treatment to the pharmaceutical approach
[40:07] Getting adequate protein through plant-based foods
[42:03] How to keep people motivated to continue with major dietary adjustments.
[46:48] Not all diets are created equal.
[49:06] RA:" more GIT destruction than a chronic gut disorder"
[50:16] Medication: biggest predictor of Paddison Program success or failure.
[53:50] Clint's thoughts on Fish Oil.
[55:30] Experience with other supplementation for RA.
[1:02:22] Clint's future vision
Research Explored in This Podcast
Moreira A, Texeria T, Ferriera A et al. Influence of a high-fat diet on gut microbiota, intestinal permeability and metabolic endotoxaemia. Br J Nutr. 2012 Sep;108(5):801-9
Suzuki T, Hara H. Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats. Nutrition & Metabolism20107:19
Serino M, Luche E, Gres S. et al. Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota. Gut. 2012 Apr; 61(4): 543–553.
Velasquez O, Tso P, Crissinger K. Fatty acid-induced injury in developing piglet intestine: effect of degree of saturation and carbon chain length. Pediatr Res. 1993 Jun;33(6):543-7.
Devkota S, Wang Y, Musch M. et al. Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10−/− mice. Nature 2012 July 5;587:104-108
Kirpich I, Feng W, Wang Y. et al. The Type of Dietary Fat Modulates Intestinal Tight Junction Integrity, Gut Permeability, and Hepatic Toll-Like Receptor Expression in a Mouse Model of Alcoholic Liver Disease. Alcohol Clin Exp Res. 2012 May; 36(5):8435-846
Lindmark T, Kimura Y, Artursson P. Absorption Enhancement through Intracellular Regulation of Tight Junction Permeability by Medium Chain Fatty Acids in Caco-2 Cells. J Pharmacol Exp Ther 1998 Jan 1;284(1):362-369
Hietbrink F, Besselink M, Renooij W. et al. Systemic inflammation increases intestinal permeability during experimental human endotoxemia. Shock. 2009 Oct;32(4):374-8
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