Evidence seems to suggest that pyridoxine and pyridoxal are prodrugs for Pyrodoxal-5-Phosphate (P5P), and that it is the P5P which has the intended therapeutic antiemetic effect.
In the first study of its kind, researchers have evaluated the effects of vitamin B12 combined with dietary protein on methionine metabolism, placental gene expression and DNA methylation in pregnant women with low vitamin B12 status.
A recent study has found that Vitamin B3 (niacin) could play a prophylactic role in the prevention of congenital malformations.
Low hair magnesium status and high serum homocysteine levels are often seen in children with autism spectrum disorders (ASD). Researchers recently confirmed these findings and hypothesise that magnesium may play a critical role in homocysteine metabolism and methylation.
N-acetyl-cysteine (NAC) is a known precursor for glutathione (GSH). This study looked at the impact of NAC on GSH status for detoxification in older populations.
A recent clinical trial sought to investigate the effects of CoQ10 supplementation on serotonin levels and depressive symptoms in patients with fibromyalgia.