Research is still emerging, however with the current evidence at hand, we are starting to get a solid understanding of the exact mechanisms behind this interesting food intolerance, which is often misdiagnosed and underestimated due to its multifaceted symptom presentation.
On analysing the scientific basis for the efficacy of S-Adenosylmethionine (SAMe), a recent comprehensive review shows the beneficial effect of supplemental SAMe as a potential alternative to or adjunctive therapy for use with antidepressants.
S-adenosylmethionine (SAMe) is integral to cellular metabolism and as the major methyl donor in the body. SAMe is involved in the methylation of a diverse range of compounds including phospholipids, DNA, RNA, proteins and neurotransmitters. It is also involved in two other important pathways – transsulfuration which produces glutathione, and aminopropylation which synthesises polyamines.